Maternal Floor Infarct

Note remote infarct black arrow and more acute to subacute infarct short white arrow in the same section.

Maternal floor infarct.

Maternal floor infarction mfi is underrecognized and likely occurring at a higher frequency than previously reported. Maternal floor infarction abbreviated mfi is a pathology of the placenta. It has a very high recurrence rate and carries a significant risk or fetal demise. Maternal floor infarction is a relatively rare condition characterized clinically by severe early onset fetal growth restriction with features of uteroplacental insufficiency.

It is also known as massive perivillous fibrin deposition. B maternal surface of placenta with diffuse dull brown appearance and remote retroplacental hematoma between arrows indenting the parenchyma. Mfi is associated with an increased risk of fetal demise and severe growth restriction. Maternal floor infarction is a rare placental lesion of unknown etiology and is often associated with sudden intrauterine fetal demise and intrauterine growth restriction.

Low maternal blood volume may contribute to the low blood flow because maternal hemoglobin values were often abnormally high in gravidas in whom floor infarcts developed. It is characterized by massive and diffuse fibrin deposition along the decidua basalis and the perivillous space of the basal plate. Definition general massive deposition of intervillous fibrin that entrap the villi of the basal plate extending to a thickness of at least 3 mm may be accompanied by massive perivillous fibrin deposition associated with recurrent abortions stillbirth fetal growth restriction or neurologic impairment. Hello ladies i am new to the forum after 3 losses just found out i have maternal floor infarction.

Placental dysfunction appears late in the process of the disease and the lesion develops rapidly within hours. The disorder was relatively frequent in the present study being present in nearly one of every 200 placentas. Acute chorioamnionitis which can damage the decidua had twice the expected frequency in gravidas with floor infarcts. Mortality was high with 17 per cent of the fetuses being stillborn.

In this study of mfi and the related placental disorder massive perivillous fibrin deposition mfd semiquantitative histologic criteria for these diagnoses are defined and rates of iugr and recurrence are assessed. Maternal floor infarction mfi is a poorly understood placental lesion reportedly associated with intrauterine growth restriction iugr and recurrence. It is formally known as placental maternal floor infarction. The fibrin in floor infarcts often extends into the intervillous space where it envelops villi causing them to become atrophic.